Isotopically Labeled Compounds
Medchemexpress LLC Prazosin-d8 | 1006717-55-0 | 98.0% | 1 MG
Prazosin-d8 is a deuterium-labeled analog of Prazosin. It acts as an alpha-adrenergic blocker and is a sympatholytic drug primarily used for the treatment of high blood pressure, anxiety, PTSD, and panic disorder.
- Deuterium labeled Prazosin
- Functions as an alpha-adrenergic blocker
- Sympatholytic drug
- Used to treat high blood pressure, anxiety, PTSD, and panic disorder
- Can be utilized as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may influence pharmacokinetic and metabolic profiles
Medchemexpress LLC β-Dihydroequilin-d4 | 350819-99-7 | 99.0% | 274.39 | 1 MG
β-Dihydroequilin-d4 is a deuterium labeled β-Dihydroequilin, primarily used as a laboratory chemical. This compound incorporates stable heavy isotopes of hydrogen, carbon, and other elements, which are utilized as tracers for quantitation during drug development processes. Deuteration has been shown to potentially influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled β-Dihydroequilin
- For research in isotope-labeled compounds
- Aids in drug quantitation during development
- May impact drug pharmacokinetic and metabolic profiles
- Ships at room temperature for less than two weeks
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Appears as a solid
Medchemexpress LLC Stearic acid-d35 | 17660-51-4 | 99.9% | 100 MG
Stearic acid-d35 is the deuterium labeled Stearic acid, a long chain dietary saturated fatty acid found in many animal and vegetable fats and oils. This compound is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Dansyl chloride-d6 (DNSCl-d6) | 1276379-68-0 | 99.47% | 5 MG
Dansyl chloride-d6 is the deuterium labeled Dansyl chloride. It is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing, and amino acid analysis. This compound is also utilized as a tracer and internal standard in various analytical methods.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2'-Deoxyuridine-13C,15N2 | 369656-76-8 | 98.1% | 1 MG
2'-Deoxyuridine-13C,15N2 is the 13C and 15N labeled 2'-Deoxyuridine, a compound that can increase chromosome breakage and decrease thymidylate synthetase activity. It is also known as a precursor in the synthesis of Edoxudine.
- Can increase chromosome breakage.
- Results in decreased thymidylate synthetase activity.
- Precursor in the synthesis of Edoxudine.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Veratrole-d6 | 24658-24-0 | 98.7% | 100 MG
Veratrole-d6 is a deuterium-labeled version of Veratrole, also known as 1,2-Dimethoxybenzene. Veratrole is an important compound found in plants, playing a role in attracting pollinators. Its release follows a circadian rhythm and is crucial for plant reproduction, species differentiation, and interactions with pollinators. Additionally, Veratrole can undergo demethylation by cytochrome P-450 in *Streptomyces setonii*.
- Isotope-labeled compound
- Targets cytochrome P450
Medchemexpress LLC Racemic anabasine-d4 | 1020719-08-7 | MFCD04039400 | >95.0% | 166.26 g/mol | C10H10D4N2 | 10 MG
Anabasine-d4 (racemic) is a deuterium-labeled isotope standard of anabasine intended for analytical and biochemical research. It is used as an internal standard or tracer for quantitation and metabolic studies, and is supplied in a small research-scale quantity for laboratory use. Not for human or clinical applications.
- Deuterium-labeled racemic anabasine
- Intended as an isotope-labeled internal standard and tracer
- Research-scale 10 mg quantity suitable for method development
- Chemical formula C10H10D4N2; molecular weight 166.26 g/mol
- CAS number 1020719-08-7; purity >95% (HPLC)
Medchemexpress LLC Nortriptyline-d3 hydrochloride | 203784-52-5 | 99.7% | 5 MG
Nortriptyline-d3 (hydrochloride) is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Deflazacort-d3 | 2280940-17-0 | 444.54 | C25H28D3NO6 | 1 MG
Deflazacort-d3 is a deuterated isotope-labeled analog of deflazacort used as an analytical internal standard for quantitative assays and mass spectrometry. Supplied in small milligram pack sizes for laboratory research; consult the certificate of analysis for purity and storage instructions.
- Deuterated internal standard for accurate quantitation in LC-MS/MS assays.
- Offered in milligram quantities suitable for analytical workflows.
- Molecular formula C25H28D3NO6; molecular weight 444.54.
- CAS number 2280940-17-0 for unambiguous identification.
- Datasheet and handling instructions available; check CoA for purity.
Cayman Chemical Flunxn-d3 1mg
An internal standard for the quantification of flunixin by GC- or LC-MS
Cayman Chemical Lyso-PAF C-16-d4 1mg
An internal standard for the quantification of PAF C-16 by GC- or LC-MS.
Medchemexpress LLC Fulvestrant-d5 | 129453-61-8 | 99.66% | 611.80 | 1 MG
Fulvestrant-d5 (ICI 182780-d5) is an isotope of Fulvestrant and a potent estrogen receptor (ER) antagonist. It effectively inhibits the growth of ER-positive MCF-7 cells and induces autophagy, demonstrating antitumor efficacy. This compound serves as a valuable tool for various analytical applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes for quantitation during drug development
Medchemexpress LLC L-arginine-13C,d4 (dihydrochloride) | 1786448-45-0 | 252.14 g/mol | C5^13CH12D4Cl2N4O2 | 1 MG
L-Arginine-13C,d4 (dihydrochloride) is an isotopically labeled L-arginine supplied for scientific research and analytical applications. It contains 13C and four deuterium labels and is provided as the dihydrochloride salt. The material is used as a tracer or internal standard for quantitative analysis by NMR, GC-MS, and LC-MS, and is intended for research use only.
- Isotopically labeled with 13C and d4.
- Provided as the dihydrochloride salt.
- Suitable as a tracer or internal standard for NMR, GC-MS, and LC-MS.
- Molecular weight 252.14 g/mol.
- Available in small analytical quantities (1 mg, 5 mg, 10 mg).
- Purity and storage information provided in the Certificate of Analysis.
Medchemexpress LLC Tentoxin-d3 | 1426437-58-2 | 417.52 | C22H27D3N4O4 | 250 UG
Tentoxin-d3 is the deuterium-labeled analogue of tentoxin, provided as a small-quantity research standard for analytical applications such as mass spectrometry and metabolic tracing. Molecular formula C22H27D3N4O4; molecular weight 417.52; CAS 1426437-58-2.
- Deuterium-labeled (d3) analogue for use as an internal standard in mass spectrometry
- Suitable for metabolic tracing and analytical method development
- Provided in a low microgram quantity for sensitive assays
- Molecular weight 417.52; molecular formula C22H27D3N4O4
- Store powder at -20°C for long-term stability
Medchemexpress LLC Simvastatin-d6 hydroxy acid, ammonium salt | 139893-43-9 | >95.0% | 459.65 | C25H37D6NO6 | 1 MG
Simvastatin-d6 hydroxy acid ammonium is a deuterium-labeled simvastatin hydroxy-acid (ammonium salt) supplied for research use as an analytical internal standard and tracer. It supports quantitative analysis in NMR, GC-MS, and LC-MS workflows and is provided in small reference quantities for laboratory analytical applications.
- Deuterium-labeled hydroxy acid ammonium salt for use as an internal standard.
- Suitable as a tracer and internal standard for quantitative NMR, GC-MS, and LC-MS analyses.
- Available in small reference quantities for analytical workflows.
- Molecular formula C25H37D6NO6; molecular weight 459.65.
- Purity >95.0% (HPLC) typical for reference standards; consult certificate of analysis for exact value.
- Store under recommended conditions indicated on the certificate of analysis.